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2 edition of value of the adjuvants to pethidine hydrochloride for the relief of pain in labour. found in the catalog.

value of the adjuvants to pethidine hydrochloride for the relief of pain in labour.

Frances Montgomery McQuitty

value of the adjuvants to pethidine hydrochloride for the relief of pain in labour.

by Frances Montgomery McQuitty

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Published .
Written in English


Edition Notes

Thesis (M.D.)--The Queens" University of Belfast, 1965.

The Physical Object
Pagination2 v
ID Numbers
Open LibraryOL19299729M

  Pethidine also causes the release of histamine from mast cells resulting in a number of allergic-type reactions. Like other opioids, pethidine binds to opioid receptors and exerts its principal pharmacological actions on the central nervous system where its analgesic and sedative effects are of particular therapeutic value.   Pethidine is controlled under the Misuse of Drugs Act (Schedule 2). Repeated use may result in dependence of the morphine type. Pethidine should be used with caution in patients with acute or chronic airflow obstruction including asthma. Pethidine should be used with caution or in reduced doses in patients with myasthenia gravis.

Synonym: 1-Methylphenylpiperidinecarboxylic acid ethyl ester hydrochloride, Meperidine hydrochloride, Pethidine hydrochloride Empirical Formula (Hill Notation): C 15 H 21 NO 2 HCl Molecular Weight: Pethidine injection is a sterile aqueous solution of 5% w/v Pethidine Hydrochloride. It also contains Water for Injections and may contain Sodium Hydroxide as a pH adjuster. Indications: it should be used with caution in patients with prostatic Relief of moderate to severe pain, as a premedication, obstetric analgesia and enhancement of analgesia.

Pethidine Hydrochloride is an opioid analgesic with pain relieving properties. This medicine is used for the relief of moderate to severe pain including pain during labour and before and during operations. 2. What you need to know before you take PETHIDINE HYDROCHLORIDE Tablets Do not take PETHIDINE HYDROCHLORIDE tablets and tell your doctor if. Pethidine hydrochloride Injection รูปแบบยาและความแรง Pethidine hydrochloride injection 50 mg/ml 1 ml ชื่อยา ภาพยา Pethidine injection 50 mg/ml 1 ml ข้อบ่งใช้1 1. Pain (Moderate to Severe) 2. Obstetric pain 3. Anesthesia; Adjunct 4. Premedication for procedure.


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Value of the adjuvants to pethidine hydrochloride for the relief of pain in labour by Frances Montgomery McQuitty Download PDF EPUB FB2

Pethidine is indicated for the treatment of moderate to severe pain, and is delivered as a hydrochloride salt in tablets, as a syrup, or by intramuscular, subcutaneous, or intravenous injection. For much of the 20th century, pethidine was the opioid of choice for many physicians; in60% of doctors prescribed it for acute pain and 22% for Other names: Meperidine (USAN US).

When the total number of doses for each drug were compared, pethidine mg gave “good” pain relief in % against % when dihydrocodeine 30 mg was used. When “paired doses” of the drugs were considered, the percentage of “good” pain relief afforded by pethidine was and that by dihydrocodeine Cited by: 1.

The use of IA meperidine resulted in lower VAS pain scores at rest but not during movement. 55 When IA or intramuscular meperidine (10 mg) was compared to morphine (1 mg) or fentanyl (10 μg) for knee arthroscopy, no difference between the groups was noted although there was a tendency for improved analgesia in the IA meperidine group.

56 The. Pethidine is a drug with powerful pain relieving properties. Pethidine Injection is used for the relief of moderate to severe pain and is used for pain relief during labour.

It may also be used to stop you from feeling pain before and during an operation and to provide continuous pain relief if needed 2. Before you are given Pethidine Injection.

An epidural can provide very good pain relief, but it's not always % effective in labour. The Obstetric Anaesthetists Association estimates that 1 in 10 women who have an epidural during labour need to use other methods of pain relief. pethidine HCl A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor.

Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration. What Pethidine Hydrochloride Injection looks like and contents of the pack Pethidine Hydrochloride Injection is a clear and colourless sterile solution in clear glass ampoules.

The ampoules are available in two sizes: 1 ml ampoule (containing 50 mg pethidine hydrochloride, the active ingredient). Lewis, Pain () The Macmillan Company New York F.M.

McQuitty, The Value of the Adjuvants to Pethidine Hydrochloride for the Relief of Pain in Labour () The Queen’s University of Belfast M.D. thesis The Australian Approved Name is pethidine hydrochloride. Empirical formula C. 2,HCl, MW: The chemical structure of pethidine hydrochloride is: DESCRIPTION.

Pethidine Injection BP contains the hydrochloride of ethyl 1methyl-4 - phenylpiperidinecarboxylate (pethidine hydrochloride) 50 mg/mL in Water for.

Pain relief in labour. Analgesic drugs may be administered, usually during the first stage of labour, to reduce the level of pain with as few side-effects as possible. Pethidine. Pethidine is one of the most commonly used, as it is effective, rapid acting and relatively safe.

It is administered by intramuscular injection and the effects last. Use of parenteral opioids for labour pain relief has been quite common, pethidine being the most commonly used drug in this group worldwide [4]. Studies on pethidine have, however, raised concerns.

Pain relief in labour - physiology and pain perceptions. Labour pain as perceived by women is a unique, subjective and complex neuro-hormonal phenomenon, which involves the interaction of physiological and psychological factors (Genesi a; Genesi b; Trout ).

Several factors have been shown to reduce pain experienced by women in labour. Pethidine is a simple and cheap drug for the management of labor pain, especially in low-resource countries with limited availability of facilities with effective methods for pain management during labor.

Its maternal adverse effects include sedation, respiratory depression, delayed gastric emptying, nausea, and vomiting. The mean interval between pethidine injection and end of delivery was ±79 min in intervention group and ±83 min in control group and the difference was not statistically significant (P=).

Relief of moderate to severe pain not responsive to non-opioid analgesics. Pre-operative medication. Analgesic adjunct in general anaesthesia. Obstetrical analgesia. Dose and method of administration Pethidine hydrochloride may be administered by subcutaneous, intramuscular.

Intramuscular pethidine is one of most common opioids used for labour analgesia. There are a number of concerns in the literature regarding the use of pethidine. Some studies have suggested that pethidine provides little or no pain relief in labour, its main effect being to cause sedation rather than analgesia.

Pethidine(Pethiscot) generic is an opioid analgesic, prescribed for moderate to severe pain, for example labor pain, before and during a surgical operation.

It changes the way the body senses pain. The pain scores were lower in the remifentanil group: median pain score at 60 min was 72 mm for meperidine and 48 mm for remifentanil (P=) and median maximum pain score during the first 2 h. Pethidine is an opioid analgesic with pain relieving properties.

This medicine is used for the relief of moderate to severe pain including pain during labour and before and during operations. Before you take Pethidine Tablets You should not take Pethidine Tablets if: • you are allergic (hypersensitive) to Pethidine or any of the. Results: There was comparable efficacy of labor pain reduction in paracetamol and pethidine after 1 h of drug administration and up till 3 h after (P pain reduction was more in.

Neonates in the pethidine group were more likely to require nursery admission (P labour pain as i.m.Indications of Pethidine.

Relief of moderate to severe pain (oral, parenteral) Preoperative medication, support of anesthesia, and obstetric analgesia (parenteral) Contraindications of Pethidine.

Presence of hypersensitivity to narcotics, Diarrhea caused by poisoning (before toxins are eliminated).1 mL Ampoules containing 25 mg Pethidine Hydrochloride.

It may be used in obstetric practice to relieve labour pain. CONTRA-INDICATIONS: Pethidine is contra-indicated in respiratory depression, obstructive pulmonary disease, hepatic insufficiency and pain following cholecystectomy and for the relief of pain associated with renal colic.